One person has died and four others were taken to hospital after a crash east of Johnstown Monday.

Provincial police say the four-vehicle collision happened at about 2:00 p.m.

They say the crash started when a tractor trailer hit a box truck in a construction zone.

Police say the driver of the box truck -- who was alone in the vehicle -- died at the scene.

Eastbound lanes of the 401 reopened at around 4:00 a.m. Tuesday. Westbound lanes remain closed.

UPDATE Road Closure: #Hwy401 EB between Hwy 16 and County Rd 22 #Cardinal - All east bound lanes are now OPEN. West bound lanes remain CLOSED. Detour Hwy 2- Reopening time unknown. ^ag

— OPPCommunicationsER (@OPP_COMM_ER) June 11, 2019